The Pride were off for the international break and it may help them regroup and get back on track against Seattle.
The Lions open their best-of-three series against Charlotte with a win at home.
Facundo Torres and Martin Ojeda provided the offense, leading Orlando City past Charlotte FC in the Lions' playoff opener.
Orlando City opens the postseason looking for a way past Charlotte's stingy defense.
The Pride drop their second straight game as the team heads into the international break.
Lions lose season finale and enter the playoffs against Charlotte, while OCB is already out of the postseason.
The teams that finished fourth and fifth in the Eastern Conference drew 1-1 and needed spot kicks to determine who advanced.
The Lions fell behind by two goals, pulled one back, and had a late equalizer overturned after video review on Decision Day.
The Lions will have to get past rival Atlanta United to assure themselves a top-four spot in the Eastern Conference on Decision Day.
International Lions, OCB set for Chicago, and the Lions host Atlanta on Decision Day.
