The Lions snapped a three-match losing streak and a five-match winless skid in league play with a win at Red Bull Arena.
The Lions have found their replacement for Daryl Dike.
The Lions blew a 2-0 lead but Junior Urso called game and Adam Grinwis won his first MLS game since 2018.
A missed Tesho Akindele penalty was the best opportunity but there were others in an unsatisfying scoreless draw at Exploria Stadium.
The Lions are unbeaten in five league matches after a much-needed win over the Chicago Fire.
After a poor first half, Orlando City was excellent for most of the second 45, pulling even and coming within inches of winning on the road.
A sloppy performance against a good Santos side results in Orlando City’s quick exit from the Leagues Cup.
Nani’s second-half goal rescues a point on the road.
Antonio Carlos’ goal was canceled out in the second half by Kieran Gibbs as the conference bottom feeders stole a point in Exploria.
The Lions showed resiliency to bounce back from a pair of one-goal deficits and Mason Stajduhar earned his first win in his MLS debut.
Angulo is suspended for tonight's match.